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It is possible that loss of GLP-1 responsivity, simultaneous with preservation of GLP-2 activity (32), may shift the enterocyte to a state favoring enhanced lipid secretion, a hypothesis that should be tested in future experiments

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Interestingly, the addition of the free radical scavengers allopurinol (an inhibitor of xanthine oxidase, an enzyme known to generate superoxide radicals), superoxide dismutase and dimethyl sulfoxide (a hydroxy radical scavenger) resulted in a significant reduction of PGN-induced lesions in rats (Moyana and Lalonde 1990b Moyana, T

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